Obesity, Intrapancreatic Fatty Infiltration, and Pancreatic Cancer.
نویسندگان
چکیده
Obesity and intrapancreatic fatty infiltration are associated with increased risk of pancreatic cancer and its precursor lesions. The interplay among obesity, inflammation, and oncogenic Kras signaling promotes pancreatic tumorigenesis. Targeting the interaction between obesity-associated inflammation and Kras signaling may provide new strategies for prevention and therapy of pancreatic cancer.
منابع مشابه
Possible Involvement of Pancreatic Fatty Infiltration in Pancreatic Carcinogenesis
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ورودعنوان ژورنال:
- Clinical cancer research : an official journal of the American Association for Cancer Research
دوره 21 15 شماره
صفحات -
تاریخ انتشار 2015